SAMe (S-adenosylmethionine)‚ a compound native to the body‚ is a critical component of many biochemical reactions‚ including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient normal aches and pains resulting from overexertion or stress. In addition‚ because SAMe is also necessary for the synthesis of neurotransmitters‚ it plays an important role in the maintenance of a positive mood. These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose‚ treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.