The natural aging process can add excessive stress on your joints. Annoying flare-ups can strike at any time. Now there's a different choice to support healthy joints. The First Choice in Premium Joint CareOsteo Bi-Flex Advanced Caplets are a revolutionary formula that contains Glucosamine, Chondroitin and MSM as well as the unique international patent pending ingredient 5-LOXIN Advanced. Taking 5-LOXIN Advanced shows improvement in joint comfort within 7 days. 5-LOXIN Advanced, Glucosamine and the Proprietary Blend Joint Shield form a dynamic combo to help:Promote MobilityRenew CartilageMaintain Healthy Connective TissueAdvanced Caplets help protect cartilage and help with annoying flare-ups while helping to renew the cellular components within joints. The Only Leading Brand with Joint Shield, Featuring 5-LOXIN Advanced5-LOXIN Advanced is a highly potent concentrated extract of the active ingredient AKBA from the herb Boswellia Serrata. 5-LOXIN Advanced contains high concentrations of AKBA, which is an important Boswellic Acid for helping with joint flare-ups. Osteo Bi-Flex Advanced is a potent synergistic combination of highly effective ingredients in Joint Care Science and the only leading brand containing Joint Shield.