Bioprocess Engineering (Hardcover: Illustrated: 576 pages)

Bioprocess Engineering, Second Edition is a comprehensive update of the world's leading introductory textbook on biochemical and bioprocess engineering. Drs. Michael L. Shuler and Fikret Kargi review the relevant fundamentals of biochemistry, microbiology, and molecular biology, introducing key principles that enable bioprocess engineers to achieve consistent control over biological activity. This edition reflects powerful advances that are transforming the field, ranging from genetic sequencing to metabolic and protein engineering. It introduces techniques with broad application to the production of pharmaceuticals, biologics, and commodities; to medical applications such as tissue engineering and gene therapy; and for solving critical environmental problems. The authors begin with the essential biological basics chemical engineers must know, including microorganism structure and functions, key metabolic pathways, enzymes, microbial genetics, kinetics, and the stoichiometry of growth. Highlights of the book's broad coverage include: new information on posttranslational processing for the manufacture of therapeutic proteins; in-depth discussions of animal cell culture processes; new information on non-carbohydrate metabolism; and a complete introduction to functional genomics and cellular engineering. Readers will learn how to apply bioprocess engineering approaches to biomedical applications; and understand thedesign nonconventional biological systems applications such as host-vector systems utilizing recombinant DNA. Bioprocess Enginnering, Second Edition makes extensive use of illustrations, examples, and problems, and contains extensive references for further reading.